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Clomiphene citrate has been used off-label to increase LH, FSH and testosterone levels in men with idiopathic infertility and/or secondary hypogonadism; however, it is not approved by the FDA for use in me
A significant barrier to such a study could be the known efficacy of clomiphene and whether the potential reductions in side effects from the single isomer formulation of enclomiphene would justify a more expensive treatmen
However, it has the unwanted effect of suppressing follicle stimulating hormone (FSH) and luteinizing hormone (LH), thus decreasing intratesticular testosterone production, consequently affecting spermatogenesis (5
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Total testosterone should be measured on at least two separate morning fasting samples, since testosterone levels show significant diurnal variation (highest in early morning) and day-to-day fluctuatio
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